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Losartan is used in the treatment of hypertension, heart failure, heart attack and diabetic kidney disease. Amlodipine is used in the treatment of hypertension and chest pain (angina).
Losartan relaxes the blood vessels which lowers the blood pressure and also reduces the workload of the heart. As a result, the heart works more efficiently. Amlodipine is a calcium channel blocker. It blocks the action of calcium on the heart and blood vessels. This lowers the blood pressure, abnormally fast heartbeat and reduces strain on the heart following a heart attack.
Fatigue, Dizziness, Orthostatic hypotension (sudden lowering of blood pressure on standing), Renal impairment, Vertigo, Increased potassium level in blood, Weakness, Anemia. Fatigue, Ankle swelling, Sleepiness, Flushing (sense of warmth in the face, ears, neck and trunk), Headache, Nausea, Dizziness, Palpitations, Edema, Abdominal pain.