CEFRINE CAPSULE

There are many different drugs in each group as well as frequent additions, but examples of the most commonly used are:

Simple analgesics
• Non steroidal anti inflammatory drugs (NSAIDS)
• Opioids (opium or morphine –like activity)
• There are many different drugs in each group as well as frequent additions, but examples of the most commonly used are:

Simple analgesics such as:
• Paracetamol (e.g. Brand names - Panadol, Panamax, Herron)
• Aspirin (e.g. Brand names - Aspro clear, Aspro, Dispirin)

Non steroidal anti-inflammatory drugs such as:
• Ibuprofen (e.g. brand name -Nurofen)
• Diclofenac Sodium (e.g. brand name – Voltaren)
• Naproxen Sodium (e.g. brand name – Naprogesic)

Weaker opioids such as:
• Combinations including codeine phosphate (e.g. brand names - Panadeine, Panadeine forte, Mersyndol, Mersyndol Daystrength, Nurofen plus)
• Tramadol hydrochloride (e.g. brand names – Tramal, Tramhexal)
• Dextropropoxyphe hydrochloride & paracetamol (e.g. brand name – Paradex, Di-gesic)

Stronger opioids such as:
• Morphine sulphate (e.g. brand names – Kapanol, MS Contin, MS Mono)
• Oxycodone (e.g. brand name- Oxycontin)
• Pethidine hydrochloride
• Tolerance and dependency

Most people can take the simple analgesics and NSAIDS without developing a dependency on these drugs.

Some problems with analgesic :
• Paracetamol – in recommended daily doses, even used long term, it is relatively harmless. In large doses it is harmful to the liver and kidneys and in rare cases can cause heart failure. It also has the potential to damage auditory nerves.
• Aspirin – is not recommended for children, pregnant women, asthmatics or those susceptible to stomach ulcers. In large doses it can be harmful to the kidneys.
• NSAIDS – in people already at risk, large doses can increase the risk of life-threatening heart or circulation problems, including heart attack or stroke. Prolonged use increases this risk. With prolonged use, there is potential for serious harm to the gastrointestinal system, including ulcers, bleeding or perforation. These conditions can be fatal and gastrointestinal effects can occur without warning at any time while taking NSAIDS. Older adults may have an even greater risk of these serious gastrointestinal side effects. Prolonged use can also affect the kidneys.
• Disclaimer: The information above is general information only and is not intended to replace medical advice. Individual circumstances vary and it is recommended that people always check with their prescribing doctor before making any changes to medication.